Presently
we
have
the
following
artciles:
-
Neem, a member of the Meliaceae family, is a botanical cousin of mahogany. According to report of an ad hoc panel of the Board on Science and Technology for International Development, "this plant may usher in a new era in pest control, provide millions with inexpensive medicines, cut down the rate of human population growth and even reduce erosion, deforestation, and the excessive temperature of an overheated globe." Neem's other descriptions, such as "nature's gift to mankind," "the tree for many an occasion," " the tree that purifies," " the wonder tree," "the tree of the 21st century," and "a tree for solving global problems," are a recognition of its versatility. Its botanic name, Azadirachta indica, derived from Farsi, "azad darakht i hindi" literally means the "free or noble tree of India," suggesting that it is intrinsically free from pest and disease problems and is benign to the environment.
Neem is an evergreen, tall, fast-growing tree, which can reach a height of 25m and 2.5m in girth. It has an attractive crown of deepgreen foliage and masses of honey scented flowers. A full-grown tree can produce 30 to 100 kg of fruits, depending on rainfall, insolation, soil type, and ecotype.
50 kg of fruit yields 30 kg of seed, which gives 6 kg of oil and 24 kg of seed cake. Neem has more than 100 unique bio-active compounds, which have potential applications in agriculture, animal care, public health, and for even regulating human fertility.
REFERENCES
Treatment % of ticks laying eggs Mean of 3 replications
Control 25 : 30 : 43 32%
0.1% 23 : 20 : 22 22%
0.2% 22 : 35 : 27 28%
0.4% 43 : 25 : 8 25%
0.6% 50 : 22 : 33 34%
0.8% 66 : 9 : 10 28%
1.0% 0 : 10 : 10 6%
Treatment Hatchability Mean Activity
Control dried out : 0 : 95 : 95 63% Highly active
0.1% 85 : 80 : 75 80% Highly active
0.2% 55 : 65 : 66 62% Highly active
0.4% 75 : 65 : 0 46% Slow to hatch, active
0.6% 50 : 60 : 12.5 41% Slow to hatch, active
0.8% 50 : 30 : 7.7 29% Slow to hatch, active
1.0% 0 : 0 : 40 13% 40% Hatch from 1 gravid tick,active
(Zero hatchability mens that no embryos developed from the eggs laid.)
Time (days Coefficient of variance Significant @ 1.0%
(ns = not significant)
1 18.7% 14.26
3 21.4% 12.67
6 28.9% 6.88
10 34.0% 5.11
13 45.4% 3.09 @ 5%
17 57.0% n.s.
21 70.7% n.s.
24 90.8% n.s.
27 149.0% n.s.
Day Control 0.1 0.2 0.4 0.6 0.8 1.0
After 17 days, the differences between treatments ceased to be significant. It is considered that there were two main reasons for this. It is accepted that after 17 days the effect of the neem oil will have diminished in spite of the closed container. The other reason is that there is a great range in the natural vitality of the newly hatched nymphs. Some ticks have more energy than others and since they are selected at random for the treatments, the law of averages dictates that there would be an average number of high vitality ticks in each treatment.
10. NEEM:A POTENTIAL BIOPESTICIDE AND SOIL CONDITIONER
by Mr. Prajapati
The Neem
Azadirachta indica A.Juss. (Syn. Melia azadirachta L . ) ; Eng- Margosa tree, Neem tree; Hindi- Neem (Meliaceaae). A common roadside tree bearing small, white and sweet scented flowers. Blossoms in early April in North Indian conditions. Tree is considered a good purifier of air, due to its large leaf area. Native of Burma but grown all over India. Oilcake, obtained from seeds, is used as a fertilizer and manure. Green twigs are used as tooth brushes for cleaning teeth, and as a prophylactic for mouth and teeth complaints. Parts of the plant are used medicinally and the leaves are placed in suit cases to repel insects and to preserve woollens. An extract of leaves is used in tooth pastes and soaps Seeds yield famous margosa oil of disagreeable garlic like flavour. Oil is said to be effective in treatment of leprosy and skin diseases. Also used as a cure for manage in dogs. Leaves in poultice are used for healing of wounds. Ripe fruits are edible. Due to its bitter taste and disagreeable odour, not removed by conventional methods, neem oil has not been utilised on an industrial scale. However, a process has recently been developed to extract the bitter constituents from neem oil. Oil thus obtained has been found to be suitable for soap making and for hydrogenation. Seed oil is also used as antiseptic and for burning purposes. Stones from fruits are used as beads in rosaries and necklaces. Azadirachtin, a substance isolated from the tree, has been found to have insect repellent and insecticidal properties. Bark yields tannin. Gum exudate from the bark is used in medicines as a stimulant, and for dyeing silk. Bark is useful in fever, nausea, vomitting and skin disease. Bitter principles of neem oil are reported to have been obtained by extraction with alcohol. The main component of the oil is nimbidin which is very bitter. Nimbidin is used for making several pharmaceutical preparations including emulsions, liquors, ointments, medicinal cosmetics such as lotions, shampoos, creams, hair tonics and gargles. Timber is used for agricultural implements and furniture.
Besides above Neem products ? Neem EC and Neem UCA have also been produced as plant growth promoter and soil conditioning agent.
NEEM EC
NEEM EC is the general- purpose botanical pesticide of choice for organic agriculture . NEEM EC is widely used in several countries around the world today either singly in Integrated Pest Management or in conjunction with synthetic pesticides. Amongst the other known botanical pesticides such as Rotenone and Pyrethrins, NEEM EC is superior due to reasons cited below. Research has shown that neem extracts can influence nearly 200 spices of insects. It is significant that some of these pests are resistant to pesticides, or are inherently difficult to control with conventional pesticides (floral thrips, diamond back moth and several leaf miners).NEEM EC belongs to the category of medium to broad spectrum pesticides. NEEM EC works by intervening at several stages of the life of an insect. It does not kill the pests instantaneously but incapacitates it in several other ways.
Mode of Action : Neem acts as a biopesticide at different levels and ways. This is very important since the farmer is used to the knock out effect of chemical pesticides. Neem does not exhibit this type of effect on pests but affects them in several other ways.
Mainly: Oviposition Deterrent Insect Growth Regulation: It is a very interesting property of neem products and unique in nature, since it works on juvenile hormone. The insect larva feeds when it grows, it sheds the old skin and again starts growing. This particular shedding of old skin is the phenomenon of ecdysis or moulting is governed by an enzyme ecdysone. When the neem components, especially Azadirachtin enter into the body of larvae, the activity of ecdysone is suppressed and the larva fails to moult, remains in the larval stage and ultimately dies. If the concentration of Azadirachtin is not sufficient, the larva manages to enter the pupal stage but dies at this stage and if the concentration is still less the adult emerging from the pupa is 100 % malformed, absolutely sterile without any capacity for reproduction.
Feeding Deterrent: The most important property of neem is feeding deterrence. When an insect larva sits on the leaf, the larva is hungry and it wants to feed on the leaf. This particular trigger of feeding is given through the maxillary glands give a trigger, peristalsis in the alimentary canal is speeded up, the larva feels hungry and its starts feeding on the surface of the leaf. When the leaf is treated with neem product, because of the presence of azadirachtin, salanin and melandriol there is an anti ? peristalitic wave in the alimentary canal and this produces something similar to vomiting sensation in the insect. Because of this sensation the insect does not feed on the neem treated surface. Its ability to swallow is also blocked.
Oviposition Deterrent: Another way in which neem reduces pests is not by allowing the female to deposits eggs. This property is known as Oviposition deterrence, and comes in very handy when the seeds in storage are coated with neem Kernel powder and neem oil. The seeds or grains obtained from the market are already infested with some insects. Even these grains could be treated with neem seed kernel extract or neem oil; after this treatment the insects will not feed on them. There will be no further damage to the already damaged grains and at the same time when the female comes to the egg laying period of its life cycle, egg laying is prevented.
Other pesticidal activity includes of need include (1) The formation of chitin (exoskeleton) is also inhibited. (2) Mating as well as sexual communication is disrupted.(3) Larvae and adults of insects are repelled. (4) Adults are sterilised. (5) larvae and adults are poisoned.
Use of neem products does not give immediate results like chemical insecticides. Some patience is required after application of neem products.
Chemistry of Ingredients of Neem
Neem plants, as do all other plants, contain several thousands of chemical constituents.Of special interest are the terpenoids are known from different parts of the neem plant. Of its biological constituents the most active and well studied compound is Azadirachtin. However, in most traditional preparations of neem as pesticide or medicine a mixture of neem chemicals are present and provide the active principles. Several different kinds of azadirachtins (A to K) have been isolated, the most abundant of which is Azadirachtin ? A. The neem terpenoids are present in all parts of the plant, in the living tissues. Recently, the site of synthesis and accumulation of the neem chemicals has been identified as secretory cells. Secretory cells are most abundant in the seed kernels. The secretory cells can be seen with iodine solution. Besides the terpenoids, neem also contains more than 20 sulphurous compounds responsible for the characteristic smell of crushed seeds and neem oil.
Toxicity: In toxicological studies carried out in the USA and Germany, different neem product were neither mutagenous nor cancerogenic, and they did not produce any skin irritations or organic alternations to mice and rates even at high concentrations. In another Canadian study, Neem was found to be harmless to Aquatic invertebrates and other non-target species.
Benefits: Neem Biopesticide (Emulsifiable Concentrate) is well suited for an ? Integrated Pest Management? (IPM) Program because of the following salient features:(1) Neem Pesticide is a natural product, absolutely non toxic, 100% biodegradable and environment mentally friend. (2) It is suited for mixing with other synthetic pesticide and in fact enhances their action. (3) None or lesser quantity of synthetic pesticides need to be used, thereby reducing the environmental load. (4) Several synthetic pesticides being single chemical compounds cause easy development of resistant species of pests. Neem consists of several compounds hence development of resistance is impossible. (5) Neem does not destroy natural predators and parasites of pests thereby allowing these natural enemies to keep a check on the pest population. (6) Neem also has systemic action and seedlings can absorb and accumulate the neem compounds to make the whole plant pest resistant. (7) Neem has a broad spectrum of action active on more than 200 spices of pests. (8) Neem is harmless to non target and beneficial organisms like pollinators, honey bees, mammals and other vertebrates.
Following are the target insects of neem:
COMMON NAME SCIENTIFIC NAME
American boll worm Heliothis armigera
Oriental armyworm Mythimna separate
Angoumis grain moth Sitorega cerealella
Pink Cotton boll worm Petinophora gossypiella
Bark eating caterpillar Indarbela quadrinotata
Pod fly Melanogromyza obtusa
Beet leaf bug Piesma quqdratum
Pulse beetle Callosobruchus chinensis
Brown planthopper Nilaparvata lugens
Pulse bruchid Callosbruchus maculates
Cabbage butterfly Pieris brassicae
Red boll worm Rabila frontalis
Chafer beetle Apogonia blancharid
Red hairy caterpillar Amsacta albistriga
Citrus leafminer Phyllocnistis citrella
Reniform nematode Rotylenchulus reinform
Confused flour beetle Tribolium confusum
Rhinoceros beetle Oryctes rhinoceros
Corn aphid Rhopaloispum maidis
Rice moth Corcyra cephalonica
Cotton aphid Aphis gossypii
Rice skipper Pelopidas mathias
Dessert locust Schistocera gregaria
Root knot nematode Melodidogyne incognita
Diamond black moth Plutella xylostella
Root knot nematode Meloidogyne javanica
Diamond moth Plutella maculipennis
Root lesion nematode Pratylenchus genus
Gall midge Orseolis oryzae
Rust red flour beetle Tribolium castaneum
Grain borer Rhizopertha dominica
Saw toothed grain beetle Oryzaephilus surinamensis
Gram / pod borer caterpillar Heloithis armigera
Scale insect Saissetia nigra
Green leafhopper Nephotettix appicalis
Serpentine leafminer Liriomyza trifolli
Green peach aphid Myzus persicae
Shoot/ fruit borer Earias vittela
Groundnut leafminer Stomopteryx nertaria
Seleron persicae Spotted boll worm
(cotton boll worm ) Erias fabia, E. insulana E. vitella
Groundnut leafminer Stomopteryx netaria
Stem borer Scirpophaga incertulas
Gypsy moth Lymantria dispar
Stem fly Melanagromyza phaseoli
Hairy caterpillar Amsacta moorei
Stunt nematode Tylenchorhynchus brassicae
Khapra beetle Trogoderma granarium
Sugarcane aphid Melanaphis sacchaari
Leaf folder / roller Cnaphalocrocis medicella
Surface grasshopper Chrotogonus trachypterus
Leafminer Aproaerema modicella
Termite Microtermes species
Leafhopper Nephotettix virescenes
Tobacco caterpillar Spodoptera litura
Lesser grain borer Rhizzopertha dominica
White backed planthopper Sogatella furcifera
Mexican bean beetle Epilachna variverstis
White fly Bemisia tabaci
Migratory locust Locusta migratoria
Mustard aphid Lipaphis erysimi
Mustard saw fly Athalia lugens proxima
Mustard webworm Crocidomia binotalis
NEEM UCA
Urea is the major source of nitrogenous fertiliser used in Agriculture. It is estimated that out of the total quantity of urea applied to crops, about 50- 70% is lost in various forms, thereby reducing the availability of nitrogen to crops. There is an age old practice in India of blending neem cake with urea. Based on this principle is our Urea coating agent NEEM UCA, a concentrated easy to use formulation. When NEEM UCA IS coated on urea, it forms a fine coating and protects the loss of Nitrogen by denitrification ensuring regulated continuous availability of nitrogen for a longer period, as per the requirement of crops.
Mode of Action: When uncoated urea is applied to the soil, the urea (Amide) nitrogen is rapidly converted to ammoniacal nitrogen and subsequently to nitrite and nitrate forms. Nitrogen in these forms, besides being absorbed by plants, is also rapidly lost from the soil due to leaching, run off, volatilization and denitrification. When NEEM UCA coated urea is applied to soil, the neem triterpenes inhibit the activity of nitrifying bacteria resulting in delayed transformation of ammoniacal nitrogen into nitrite nitrogen. This ensures slow and continuous availability of nitrogen matching the requirements of crop plant during their life cycle.
Benefits: (1) Ready to use, economical and easy to apply. (2) Ensures slow and continuous availability of nitrogen to crops. (3) Reduces nitrogen loss from urea due to leaching and denitrification. (4) Protects crops from soil borne pests.
Method of Application: (1) Spread 50 Kg urea in the shade on a clean surface. (2) Mix evenly 250 gm NEEM UCA ensuring proper spreading on urea. (3) Rub urea NEEM UCA thoroughly by hand to get a uniform coating. For larger quantities of urea, suitable mixers can be used. (4) Allow coated urea to dry till it is free flowing and ready to use.
Top
flu-like virus through a Hong Kong apartment block, a top health official said on Tuesday as the disease spread to one of the city's crowded new towns.
At least three more people died in Beijing from SARS than officially reported, doctors in Beijing said on Tuesday as fears spread and hospitals disclosed suspected cases not previously revealed.
Hong Kong Deputy Director of Health Leung Pak-yin told a radio programme cockroaches may have carried infected waste from sewage pipes into apartments at Amoy Gardens in densely populated Kowloon district.
If proved true, it would represent an alarming development in the swiftly spreading epidemic in Hong Kong, a city of seven million people filled with densely populated apartment blocks.
"The drainage may be the reason. It is possible that the cockroaches carried the virus (from the drainage pipes) into the homes," Leung said.
SARS raced through a block in Amoy Gardens in late March, infecting nearly 300 people and forcing residents in the building and others in the complex to flee in panic. The speed of the outbreak has baffled health officials.
----------------
At Rym Exports, we are instrumental in providing Quality Potent Neem Oil & other Herbal Oils to manufacture an 100 % effective Cockroach Repellent Solution.
Kindly contact us for Prices.
1.Neem
for
Sustainable
Development
and
Environmental
Conservation
:
Indian Perspective
By: Dr. Ramesh C. Saxena
Indian Perspective
By: Dr. Ramesh C. Saxena
The
population
of
India
has
already
crossed
the
one
billion
mark.
Providing
adequate
food
entitlements,
safeguarding
public
health,
meeting
fuel
and
firewood
needs,
and
at
the
same
time
preventing
deforestation
and
conserving
the
environment,
and
slowing
down
the
population
growth
will
be
daunting
challenges
in
the
coming
decades.
Although
"green
revolution
technologies"
have
more
than
doubled
the
yield
potential
of
cereals,
especially
rice
and
wheat
in
India,
these
high
- input
production
systems
requiring
large
quantities
of
fertilizers,
pesticides,
irrigation,
and
machines,
disregard
the
ecological
integrity
of
land,
forests,
and
water
resources,
endanger
the
flora
and
fauna,
and
cannot
be
sustained
over
generations.
Future
food
security
and
economic
development
would
depend
on
improving
the
productivity
or
biophysical
resources
through
the
application
of
sustainable
production
methods,
by
improving
tolerance
of
crops
to
adverse
environmental
conditions,
and
by
reducing
crop
and
post-harvest
losses
caused
by
pests
and
diseases.
Appropriate
technologies,
which
do
not
assault
the
nature,
would
have
key
roles
to
play
in
ensuring
food
security,
in
improving
public
and
animal
health,
and
in
rehabilitation
the
environment
to
safeguard
the
well
being
of
the
posterity.
The
future
must
look
to
natural
ways
and
process
for
augmenting
agricultural
productivity.
In
fact,
all
development
efforts
and
activities,
including
pest
management,
should
be
within
well-defined
ecological
rules
rather
than
within
narrow
economic
gains.
Sustainable
agricultural
systems
must
be
efficient
(i.e.
effective
and
economically
rewarding)
and
ecologically
sound
for
long-term
food
sufficiency,
equitable
in
providing
social
justice,
ethical
in
respecting
both
future
generations
and
other
species,
and
also
lead
to
employment
and
income-generating
opportunities.
For
India,
the
use
of
neem
may
provide
a key
component
in
ensuring
sustainable
agricultural
systems,
including
pest
and
nutrient
management,
animal
health,
human
health,
and
environmental
conservation.
Neem, a member of the Meliaceae family, is a botanical cousin of mahogany. According to report of an ad hoc panel of the Board on Science and Technology for International Development, "this plant may usher in a new era in pest control, provide millions with inexpensive medicines, cut down the rate of human population growth and even reduce erosion, deforestation, and the excessive temperature of an overheated globe." Neem's other descriptions, such as "nature's gift to mankind," "the tree for many an occasion," " the tree that purifies," " the wonder tree," "the tree of the 21st century," and "a tree for solving global problems," are a recognition of its versatility. Its botanic name, Azadirachta indica, derived from Farsi, "azad darakht i hindi" literally means the "free or noble tree of India," suggesting that it is intrinsically free from pest and disease problems and is benign to the environment.
Neem is an evergreen, tall, fast-growing tree, which can reach a height of 25m and 2.5m in girth. It has an attractive crown of deepgreen foliage and masses of honey scented flowers. A full-grown tree can produce 30 to 100 kg of fruits, depending on rainfall, insolation, soil type, and ecotype.
50 kg of fruit yields 30 kg of seed, which gives 6 kg of oil and 24 kg of seed cake. Neem has more than 100 unique bio-active compounds, which have potential applications in agriculture, animal care, public health, and for even regulating human fertility.
Neem
has
had
a long
history
of
use
primarily
against
household
and
storage
pests
and
to
some
extent
against
crop
pests
in
India.
With
the
advent
of
broad-spectrum,
toxic
insecticides,
such
as
DDT,
the
use
of
neem
in
crop
protection
declined.
However,
over
the
past
two
decades,
neem
has
been
come
under
close
scientific
scrutiny
"as
a source
of
unique
natural
products
for
IPM,
medicine,
industry,
and
other
purposes.
In
spite
of
high
selectivity,
neem
derivatives
affect
400
to
500
species
of
mites
and
ticks,
nematodes,
and
even
noxious
snails
and
fungi,
and
aflatoxin
- producing
Asergillus
spp.
Results
of
large-scale
field
trials
conducted
by
me
and
others
have
illustrated
the
value
of
neem-based
pest
management
for
enhancing
agricultural
productivity.
The
use
of
neem
and
fertiliser
mixtures
can
reduce
ammonia
volatilization
loss
caused
by
nitrifying
bacteria
in
soil,
thus
effecting
saving
on
fertilizers.
A large
number
of
neem-based
medicines,
pharmaceuticals,
and
toiletries
are
being
produced
today
and
are
in
great
demand
overseas.
Neem
has
scope
in
reforestation
and
agroforestry
and
rehabilitating
waster
and
degraded
lands.
It
is
useful
as
windbreaks
and
in
areas
of
low
rainfall
and
high
windspeed,
it
can
protect
crops
from
desiccation.
Neem
has
much
to
offer
in
solving
agricultural
and
public
health
problems
in
the
country,
especially
in
rural
areas.
However,
more
neem
trees
will
have
to
be
grown
to
meet
the
increasing
demand
for
insecticidal
and
industrial
uses.
The
local
peasant
community
will
have
to
be
brought
with
the
fold
of
increased
awareness
by
outreaching
and
through
interpersonal
interaction,
by
involving
'sarpanch'
or
village
chiefs,
schools,
women
groups,
and
government
and
non-government
organizations.
Field
demonstrations
and
neem
fairs
at
strategic
locations
will
have
to
be
organized
periodically
in
collaboration
with
local
bodies
or
institutions
to
evoke
the
interest
and
participation
of
target
communities.
Also,
existing
local
initatives,
if
any,
will
have
to
be
strengthened.
Strategies
for
creating
awareness
will
involve
hands-on
training
through
lectures
and
demonstrations
to
trainers,
comprising
agricultural
trainers,
foresters,
extension
personnel,
health
workers,
teachers,
journalists,
and
representatives
of
NGOS,
youth
and
women
groups,
who
would
then
have
a multiplier
effect
in
target
areas.
They
will
have
to
be
taught
how
to
harvest,
collect
and
process
neem
seed,
grow
and
plant
seedling,
and
use
various
neem
materials
for
pest
management.
The
distribution
of
raw
materials
will
have
to
be
guaranteed
by
establishing
nodal
agencies
in
target
areas.
These
activities
will
create
employment
opportunities
and
also
generate
income.
The
complex
molecular
structure
of
bio-active
neem
compounds
precludes
their
chemical
synthesis
economically.
Therefore,
even
the
chemical
industry
will
have
to
rely
on
the
use
of
raw
material.
With
growing
demand
for
natural
pest
control
materials,
the
use
of
neem
products
is
becoming
popular
worldwide.
In
the
next
decade,
it
is
expected
that
global
neem
trade,
comprising
neem-
based
pest
control
materials,
medicines,
pharmaceuticals,
and
toiletries
will
grow
to
more
than
$500m.
Herein
lies
a huge
window
of
opportunity
to
benefit
by
growing
and
harnessing
neem
not
only
for
local
use
but
also
for
export
to
regions
and
countries
where
neem
does
not
thrive.
2.
NEEM
: THE
WONDER
TREE
By
Dr.
Rahman
The neem tree (Azadirachta indica) is regarded as one of mother nature's gift to the world. In India , it is commonly found in house compounds in both villages and cities. Green twigs are used as toothbrushes to combat teeth decay. Its extracts have a powerful pesticidal activity and are used by both households and farmers to control a wide variety of pests (insects, fungi, bacteria, viruses, nematodes, rodents etc.). These extracts have considerable antiseptic affects and are used as a skin care agent in soaps and shampoos. The leaves are often mixed with rice and consumed as a cure all and prophylactic against bacterial and helminthic infections. Neem leaf pastes are used to repair scarred skins arising from the effects of chicken pox. Not surprisingly, many believe that the neem tree itself can ward off demons.
The neem tree (Azadirachta indica) is regarded as one of mother nature's gift to the world. In India , it is commonly found in house compounds in both villages and cities. Green twigs are used as toothbrushes to combat teeth decay. Its extracts have a powerful pesticidal activity and are used by both households and farmers to control a wide variety of pests (insects, fungi, bacteria, viruses, nematodes, rodents etc.). These extracts have considerable antiseptic affects and are used as a skin care agent in soaps and shampoos. The leaves are often mixed with rice and consumed as a cure all and prophylactic against bacterial and helminthic infections. Neem leaf pastes are used to repair scarred skins arising from the effects of chicken pox. Not surprisingly, many believe that the neem tree itself can ward off demons.
The
pesticidal
and
medicinal
properties
of
extracts
from
the
neem
tree
have
been
exploited
for
at
least
the
last
2500
years.
Sanskrit
texts
dating
back
to
the
sixth
century
BC,
document
the
microbicidal
and
prophylactic
effects
of
neem
extracts.
Charaka
in
the
6th
Century
BC
recommended
the
oral
consumption
of
neem
extracts
to
ward
off
pimples,
leprosy
and
edema.
Sushruta
in
the
5th
century
BC
recommended
the
use
of
neem-leaf
smoke
for
fumigation
and
maintenance
of
general
hygiene.
He
also
recommended
it
as
a "krimihara",
an
agent
effective
against
insects,
grubs
and
maggots
and
detailed
the
ability
of
neem
leaves
to
cure
gangrenous
and
otherwise
difficult
to
cure
wounds.
The
neem
tree
appears
to
be
a biochemical
factory
producing
a mixture
of
over
135
biologically
active
compounds.
As
a pestticide,
the
oil
from
neem
seeds
are
believed
to
break
the
life
cycle
of
pests
and
deters
them
from
feeding
and/or
hatching.
Studies
have
shown
that
active
compounds
iin
the
oil
inhibited
the
secretion
of
hormones
into
the
blood
inhibting
the
moulting
and
reproductive
function
in
insects.
Neem
oil
is
known
to
be
active
on
over
400
insect
pests.
It
has
for
example
been
found
to
be
effective
against
fleas,
head
lice,
ticks,
termites,
plague
locusts,
mosquitoes
and
sheep
blow
flies.
It
is
believed
to
be
particularly
active
against
chewing
and
sucking
insects
such
as
caterpillars
and
beetle
larvae.
Neem
extracts
have
also
been
shown
to
be
effective
against
nematode
pests.
Neem
cake,
the
by
product
from
neem
seed
processing
appears
to
be
effective
on
nematodes,
snails
and
certain
fungi.
The
neem
tree
and
its
extracts
surprisingly
appear
to
be
benign
to
bees
and
other
nectar
feeding
insects.
Seed
extracts
are
not
known
to
have
any
toxic
effect
on
plants,
mammals
and
birds
and
in
fact
in
studies
by
the
US
EPA,
no
LD-50
could
be
established
even
at
high
doses.
These
remarkable
properties
have
attracted
considerable
interest
from
both
researchers
and
pharmaceutical
companies.
This
renewed
interest
in
neem
created
no
more
than
amusement
in
India
where
the
beneficial
properties
of
neem
have
been
known
for
countless
generations.
This
mood
however
has
recently
changed
with
Grace
Horticultural
Products,
a unit
of
Grace
Speciality
Chemicals
(USA)
acquiring
the
patent
and
trademark
rights
to
produce
and
sell
insecticidal
neem
extracts.
Their
product,
Margosan-O
Concentrate,
is
protected
under
US
patent
No.
5124349.
In
1995,
a group
led
by
Mr.
Jeremy
Rifkin,
president
of
the
Foundation
of
Economic
Trends
in
the
US,
Dr.
Vandana
Shiva
of
the
Research
Foundation
for
Science
Technology
and
Natural
Resource
Policy
and
Professor,
Nanjundaswamy
of
the
Karnataka
Rajya
Ryot
Sangha
in
India
contested
the
decision
of
the
US
Patent
and
Trademark
Office.
They
claim
that
the
neem
product
has
long
been
used
as
a pesticide
in
India
and
is
not
a new
invention
as
claimed
under
the
patent.
They
claim
that
Grace's
patent
does
not
satisfy
the
criterion
that
the
invention
must
not
be
obvious
to
one
of
ordinary
skill
in
the
art.
They
assert
that
the
Grace
process
only
slightly
differs
from
that
used
by
farmers
in
India.
Grace
on
the
otherhand
claims
that
its
patent
relates
to
a formulation
based
on
neem-seed
extract.
They
assert
their
formulation
overcomes
the
problems
associated
with
the
instability
of
azadirachtin,
the
primary
active
pesticidal
ingredient
from
the
plant,
in
traditionally
used
water
or
alcohol
based
emulsions.
Further
the
awarding
of
patents
based
on
the
purification
or
modification
of
naturally
occurring
substances
is
not
new.
For
example,
in
1979,
the
US
Court
of
Customs
and
Patent
Appeals
reversed
a decision
by
the
Patent
and
Trademark
Office
to
award
a patent
for
a compound
purified
from
strawberries.
In
fact,
more
than
40
patents
have
already
been
award
for
inventions
relating
to
a compound
found
in
neem
seeds
alone.
Regardless
of
its
outcome,
the
legal
battle
ensuing
between
Grace
and
its
opponents
will
have
significant
ramifications
for
the
natural
products
industry.
Rifkin
and
partners
assert
that
the
patent
and
other
similar
patents
will
mean
that
"indigenous
populations
around
the
world,
will
be
excluded
from
freely
using
many
of
the
local
biological
resources
that
have
been
carefully
developed
and
nurtured
over
hundreds
of
years".
It
has
even
been
claimed
that
in
a worst
case
scenarios
that
indigenous
farmers
would
have
to
pay
royalties
to
carry
on
their
centuries-old
farming
practices.
Unfortunately
the
latter
argument
fails
to
consider
that
no
universal
patent
exists
and
as
such
Grace's
patent
is
not
valid
in
India.
Indian
farmers
can
thus
choose
to
pay
a premium
for
Grace's
formulation
or
continue
to
produce
their
own.
As
a result
of
this
case,
developing
countries
are
now
more
concerned
about
the
consequences
of
the
loss
in
sole
proprietary
of
a biological
resource.
Recently,
a senior
official
from
the
Indian
Council
of
Agricultural
Research
voiced
his
concern
on
the
"pilfering"
of
traditional
plant
varieties
from
India.
"The
neem
is
ours
and
nobody
can
take
it
away".
His
claim
may
be
a case
of
closing
the
door
after
the
horse
has
bolted
and
is
indeed
somewhat
curious,
given
that
neem
trees
have
been
successfuly
grown
in
over
17
countries.
They
can
in
fact
be
obtained
here
in
Singapore.
The
Indian
government
is
in
the
process
of
formulating
a Plant
Varieties
Protection
Act
which
will
seek
to
protect
over
2,300
currently
unprotected
Indian
plant
varieties.
Whether
other
countries
follow
India's
lead
will
certainly
have
a significant
influence
on
both
research
and
production
of
natural
products.
:
Reproduced
with
permission
from
Dr.Mallick
Rahman
Top
3. NEEM OIL: FACTS & EXPERIENCES By Mr Larry Evans
I can only tell you of my experience with Neem Oil. I cannot recommend Neem oil because our government ( USA ) has not approved its use on orchids or on any plants. When I refer to Neem oil, I mean pure Neem Oil as pressed from the seeds of the Neem tree. I have never used any product with Neem oil in it. I don't know that it would be as safe as pure Neem oil.
3. NEEM OIL: FACTS & EXPERIENCES By Mr Larry Evans
I can only tell you of my experience with Neem Oil. I cannot recommend Neem oil because our government ( USA ) has not approved its use on orchids or on any plants. When I refer to Neem oil, I mean pure Neem Oil as pressed from the seeds of the Neem tree. I have never used any product with Neem oil in it. I don't know that it would be as safe as pure Neem oil.
Where
does
Neem
oil
come
from?
Originally
it
came
from
India.
The
Indian
natives
have
been
using
Neem
for
about
3000
years
as
an
internal
remedy
as
well
as
an
ingredient
in
tooth
paste,
soap,
shampoo,
cosmetics
and
skin
creams.
I
have
never
used
a product
in
the
greenhouse
whose
effects
were
as
efficient
and
long
lasting
as
Neem.
Insecticides
and
fungicides
that
I had
previously
used
were
a short-term
fix
- about
two
weeks.
And
the
smell
was
offensive
and
lasted
for
days.
But
it
was
what
was
available
to
keep
a clean
insect
free
greenhouse
even
if
the
fumes
from
most
insecticides
caused
me
to
have
allergic
reactions.
Due
to
a long
term
illness,
my
greenhouse
became
a disaster
area.
In
January,
as
the
phalaenopsis
were
spiking,
the
mealy
bugs
moved
in
by
the
thousands.
About
75%
of
the
mature
plants
had
fire
ants
in
the
pot.
Scale
was
rampant.
We
had
snails
and
slugs
so
big
they
looked
dangerous.
Toxic
sprays
did
not
get
rid
of
them
completely.
The
first
time
I used
Neem
oil
(1
oz.
to
1 gallon
of
water
+ few
drops
of
dishwashing
liquid),
I sprayed
every
plant,
bench,
walkway
and
under
every
bench.
In
a few
days
there
was
a definite
improvement.
I waited
2 weeks
and
sprayed
again.
I kept
a close
eye
on
the
plants,
no
mealy
bugs,
scale
and
best
of
all
the
fire
ants
were
gone.
And
no
more
slugs
and
snails.
I
didn't
spray
again
for
six
months.
I found
a snail
and
a slug,
no
other
'live
stock',
but
I decided
to
spray
everything
again.
The
beauty
part
of
using
Neem
oil
is
that
you
don't
have
to
wear
protective
clothing
or
special
breathing
equipment
and
there
are
no
sickening
odors.
Neem
oil
does
have
an
odor,
best
described
as
'kind
of
like
onion
soup'.
However,
the
odor
only
lingers
for
a short
time.
How
does
Neem
get
rid
of
insects?
Most
insects
die
shortly
after
spraying.
Those
remaining
become
sterile
and
do
not
reproduce.
I've
heard
a story
of
2 desert
locusts,
2 grape
leaves
and
2 bell
jars.
One
grape
leaf
was
sprayed
with
an
insecticide,
the
other
with
Neem.
One
locust
and
one
grape
leaf
were
put
under
each
bell
jar.
The
locust
ate
the
toxic
leaf
and
died.
The
other
locust
refused
to
eat
the
Neem
sprayed
leaf
and
starved
to
death.
From
my
experience
the
story
could
be
true.
I believe
it
is
better
if
you
can
prevent
the
insect
from
eating
the
plant,
than
to
let
them
eat
the
plant
and
then
die.
It
takes
years
to
lose
the
damaged
leaves
on
most
orchids.
Flowers
can
be
ruined
before
the
critters
will
die
from
insecticide.
I've
not
been
disappointed
with
Neem
Oil.
I'm
sure
that
many
who
read
this
will
be
sceptical
because
of
the
'do
everything'
claim.
We
have
a cat
that
has
grown
up
in
the
greenhouse.
Neem
hasn't
bothered
her
at
all.
Panzie
greets
all
comers
and
we
certainly
would
not
use
anything
that
would
hurt
her.
We
also
used
Neem
on
my
daughter's
dog,
a Shar-pei.
The
dog
was
biting
and
chewing
her
fur
and
making
sores
and
bald
spots
all
over
her
coat.
The
veterinarian
said
she
had
hair
mites.
There
is
a treatment
for
this
- a
series
of
6 dips
at
$65.00
per
dip
and
only
a 50%
chance
of
a cure.
I suggested
that
she
try
using
a 'Neem
rinse'
after
bathing
the
dog,
using
a 1
oz.
to
1 gallon
of
water.
This
treatment
was
followed
for
three
weeks.
The
dog
has
stopped
chewing
herself
and
has
grown
back
a full
glossy
coat.
It
is
also
harmless
on
people.
A lady
in
our
orchid
society
has
an
allergy
to
mosquito
bites.
Living
in
Florida
she
had
a problem
working
in
her
garden,
fishing
or
taking
an
evening
stroll.
She
had
used
spray
repellents
but
it
was
difficult
to
use
and
not
always
satisfactory.
She
tried
Neem
oil
and
she
swears
by
it.
When
I use
Neem
oil
I only
mix
the
amount
I will
use
within
four
hours.
Neem
is
very
biodegradable
and
will
start
to
break
down
quickly.
If
it
is
kept
in
the
refrigerator
at
approximately
40F
the
shelf
life
is
extended.
As
any
organic
oil,
it
will
turn
rancid.
How
soon
will
depend
on
the
storage
temperature.
We
have
used
pure
Neem
oil
on
cattleya,
dendrobium,
phaleanopsis,
oncidiums,
vanilla,
vanda,
peristeria,
etc.
We
have
detected
no
damage
to
any
of
these
plants.
Reproduced
with
permission
from
Mr
Larry
Evans
1.
Pure
Neem
Oil
will
retain
its
potency
much
longer
if
stored
at
about
40°
F in
a low
light
area
such
as
a refrigerator.
2.
Do
not
mix
anything
with
Neem
oil
until
you
are
ready
to
use
it.
Mix
only
the
amount
of
Neem
oil
you
will
use
in
4 to
6 hours.
3.
A new
batch
of
Neem
oil,
water
and
a little
soap
(according
to
the
label)
should
be
mixed
each
time
you
are
going
to
spray.
4.
The
soap
(dishwashing
detergent)
is
used
to
help
emulsify
the
oil.
If
no
soap
is
used
the
Neem
will
not
mix
into
solution
with
the
water
and
spraying
will
not
be
effective.
5.
Spray
the
complete
plant
including
the
top
of
the
potting
media.
Spray
benches,
walkways
and
any
surface
over
which
an
insect
might
travel.
6.
A mixture
of
1 oz.
to
1 gallon
of
water
should
be
used
for
spraying.
A weaker
solution
may
be
used
as
a maintenance
spray.
It
is
impossible
to
gie
a definite
schedule
for
spraying,
however
a "close
eye"
will
help
each
person
to
adjust
a timetable
to
maintain
clean
plants.
You
will
probably
not
have
to
spray
as
often
with
Neem
as
with
toxic
insecticides.
Reproduced
with
permission
from
Mr
Larry
Evans
Properties
of
Azadirachtin
( obtained
from
Seeds
of
Neem
Tree
)
Following
Details
Reproduced
Below
With
Permission
From
Cornell
University.
Azadirachtin
Regulatory
Status
Azadirachtin
is
registered
in
the
United
States
as
a general
use
pesticide
with
a toxicity
classification
of
IV
(relatively
non-toxic).
Check
with
specific
state
regulations
for
local
restrictions
which
may
apply.
Products
containing
azadirachtin
must
bear
the
signal
word
"Caution"
or
"Warning"
on
their
label
(1).
Introduction
The
key
insecticidal
ingredient
found
in
the
neem
tree
is
azadirachtin,
a naturally
occurring
substance
that
belongs
to
an
organic
molecule
class
called
tetranortriterpenoids
(6).
It
is
structurally
similar
to
insect
hormones
called
"ecdysones," which control the process of metamorphosis as the insects pass from
larva to pupa to adult. Metamorphosis requires the careful synchrony of many hormones and other physiological changes to be successful, and azadirachtin seems to be an "ecdysone
blocker." It blocks the insect's production and release of these vital hormones. Insects then will not molt, thus breaking their life cycle (4, 5).
"ecdysones," which control the process of metamorphosis as the insects pass from
larva to pupa to adult. Metamorphosis requires the careful synchrony of many hormones and other physiological changes to be successful, and azadirachtin seems to be an "ecdysone
blocker." It blocks the insect's production and release of these vital hormones. Insects then will not molt, thus breaking their life cycle (4, 5).
Azadirachtin
may
also
serve
as
a feeding
deterrent
for
some
insects.
Depending
on
the
stage
of
life-cycle,
insect
death
may
not
occur
for
several
days.
However,
upon
ingestion
of
minute
quantities,
insects
become
quiescent
and
stop
feeding.
Residual
insecticidal
activity
is
evident
for
7 to
10
days
orlonger,
depending
on
insect
and
application
rate
(1,2).
Azadirachtin
is
used
to
control
whiteflies,
aphids,
thrips,
fungus
gnats,
caterpillars, beetles, mushroom flies, mealybugs, leafminers, gypsy moths and
others on food, greenhouse crops, ornamentals and turf (2, 11).
caterpillars, beetles, mushroom flies, mealybugs, leafminers, gypsy moths and
others on food, greenhouse crops, ornamentals and turf (2, 11).
TOXICOLOGICAL
EFFECTS
ACUTE
TOXICITY
The
acute
oral
toxicity
in
rats
fed
technical
grade
azadirachtin
ranged
from
greater
than
3,540
mg/kg
to
greater
than
5,000
mg/kg,
the
highest
dose
tested
when
administered
undiluted to albino rats (1, 2, 3).
undiluted to albino rats (1, 2, 3).
The
acute
inhalation
toxicity
study
in
rats
exposed
to
technical
azadirachtin
showed
that
the
acute
inhalation
LD50
is
greater
than
2.41
mg/L
per
animal,
the
highest
dose
tested.
Although this figure is below the 5.0 mg/L limit test dose for an acute inhalation study, the reported concentration was the maximum dose possible under the test conditions. No
deaths occurred during the course of the study. Azadirachtin was given a toxicity classification of Category III (3).
Although this figure is below the 5.0 mg/L limit test dose for an acute inhalation study, the reported concentration was the maximum dose possible under the test conditions. No
deaths occurred during the course of the study. Azadirachtin was given a toxicity classification of Category III (3).
A
primary
eye
irritation
study
in
rabbits
exposed
to
technical
azadirachtin
was
rated
mild
to
moderately
irritating
after
instillation
of
0.1
gm
of
the
undiluted
material.
At
one
hour
post-instillation,
the
maximum
eye
irritation
score
was
15.3/110;
by
24,
48,
and 72 hours the scores were 6.2/110, 0.3/110, and 0/110, respectively. It was given a toxicity category of III (3).
and 72 hours the scores were 6.2/110, 0.3/110, and 0/110, respectively. It was given a toxicity category of III (3).
Primary
dermal
irritation
in
rabbits
when
tested
at
a single
dose
(0.5
gm)
by
applying
it
to
the
shaved
backs
of
rabbits,
did
not
cause
any
dermal
irritation
after
4 hours
of
exposure.
The
dermal
score
was
zero
for
all
treated
rabbits
at
all
examination
times.
A toxicity category of IV, mild to slightly irritating,was assigned.
A toxicity category of IV, mild to slightly irritating,was assigned.
An
acute
dermal
toxicity
study
of
rabbits
exposed
to
technical
azadirachtin
was
performed.
The
material
was
applied
for
24
hours
at
a single
dose
of
2.0
gm/kg
to
the
shaved
backs
of
the
rabbits,
that
caused
dermal
irritation
which
resolved
by
day
nine.
Azadirachtin was classified as a mild irritant (3). Another study reported the dermal LD50 for rabbits to be >2,000 mg/kg (1,2).
Azadirachtin was classified as a mild irritant (3). Another study reported the dermal LD50 for rabbits to be >2,000 mg/kg (1,2).
Dermal
sensitization
in
guinea
pigs
found
the
technical
end-use
product
to
be
categorized
as
a mild
sensitizer
when
administered
undiluted
to
albino
guinea
pigs.
The
test
material
was
considered
a weak
dermal
sensitizer
to
albino
guinea
pigs
(3).
CHRONIC
TOXICITY
A
90-day
oral
toxicity
study
in
rats
fed
levels
of
500,
2500,
and
10,000
ppm
of
azadirachtin
showed
no
signs
of
overt
systemic
toxicity
at
any
dose
level
after
90
days
of
feeding.
Mean
body
weight
was
significantly
decreased
in
the
10,000
ppm
males
and
females at weeks 3 and 4, respectively. This persisted for the duration of the 90-day feeding period (11).
females at weeks 3 and 4, respectively. This persisted for the duration of the 90-day feeding period (11).
Reproductive
Effects
Male
antifertility
activity
of
neem
leaf
extract
was
studied
in
mice,
rats,
rabbits
and
guinea
pigs
by
daily
oral
feeding
of
a cold-water
extract
of
fresh
green
neem
leaves.
The
infertility effect was seen in treated male rats as there was a 66.7% reduction in fertility after 6 weeks, 80% after 9 weeks, and 100% after 11 weeks. There was no
inhibition of spermatogenesis.
infertility effect was seen in treated male rats as there was a 66.7% reduction in fertility after 6 weeks, 80% after 9 weeks, and 100% after 11 weeks. There was no
inhibition of spermatogenesis.
During
this
period
there
was
no
decrease
in
body
weight
and
no
other
manifestation
of
toxicity
observed.
There
was
a marked
decrease
in
the
mortality
of
spermatozoa.
The
infertility in rats was not associated with loss of libido or with impotence and the
animals maintained normal mating behavior. The male antifertility activity was reversible in 4 to 6 weeks. Neem extract also shows reversible male antifertility activity in mice
without inhibition of spermatogenesis. In guinea pigs and rabbits, however, it exhibited toxicity as demonstrated by 66.6% and 74.9% mortality in guinea pigs and 80 and 90% mortality in rabbits at the end of 4 and 6 weeks, respectively (9).
infertility in rats was not associated with loss of libido or with impotence and the
animals maintained normal mating behavior. The male antifertility activity was reversible in 4 to 6 weeks. Neem extract also shows reversible male antifertility activity in mice
without inhibition of spermatogenesis. In guinea pigs and rabbits, however, it exhibited toxicity as demonstrated by 66.6% and 74.9% mortality in guinea pigs and 80 and 90% mortality in rabbits at the end of 4 and 6 weeks, respectively (9).
Teratogenic
Effects
No
information
was
found.
Mutagenic
Effects
Technical
azadirachtin
was
evaluated
for
the
potential
to
cause
gene
mutations
in
the
S.
typhimurium
strains
at
any
dose
(5,
50,
500,
5,000
micrograms/plate)
with
or
without
S-9
activation. The study was negative (3).
activation. The study was negative (3).
Carcinogenic
Effects
No
information
was
found.
Fate
in
Humans
and
Animals
No
information
was
found.
ECOLOGICAL
EFFECTS
Effects
on
Birds
No
significant
effects
on
other
wildlife
were
reported
(8).
Effects
on
Aquatic
Organisms
The
LC50
for
rainbow
trout
exposed
to
azadirachtin
is
0.48
ppm
(11).
It
may
cause
significant
fish
kill
if
large
concentrations
reach
waterways.
It
breaks
down
rapidly
(in
50-100
hours)
in
water
or
light,
and
is
not
likely
to
accumulate
or
cause
long-term
effects (8, 11).
effects (8, 11).
Effects
on
Other
Animals
(Nontarget
species)
Azadirachtin
is
relatively
harmless
to
spiders,
butterflies,
and
insects
such
as
bees
that
pollinate
crops
and
trees,
ladybugs
that
consume
aphids,
and
wasps
that
act
as
parasites
on
various
crop
pests.
This
is
because
neem
products
must
be
ingested
to
be
effective. Thus, insects that feed on plant tissue succumb, while those that feed on nectar or other insects rarely contact significant concentrations of neem products.
effective. Thus, insects that feed on plant tissue succumb, while those that feed on nectar or other insects rarely contact significant concentrations of neem products.
Another
study
found
that
only
after
repeated
spraying
of
highly
concentrated
neem
products
onto
plants
in
flower
were
worker
bees
at
all
affected.
Under
these
extreme
conditions,
the
workers
carried
contaminated
pollen
or
nectar
to
the
hives
and
fed
it
to the brood. Small hives then showed insect-growth-regulating effects; however,
medium-sized and large bee populations were unaffected (4).
to the brood. Small hives then showed insect-growth-regulating effects; however,
medium-sized and large bee populations were unaffected (4).
A
study
of
neem
products
and
their
effect
on
mortality,
growth
and
reproduction
of
earthworms
in
soils
was
conducted.
Positive
effects
on
weight
and
survival
were
found
in
soil treated with ground neem leaves and ground seed kernals under greenhouse conditions. Reproduction was slightly favored over a period of 13 weeks in a neem-enriched
substrate in rearing cages. Various neem products were incorporated in the upper 10-cm soil layer of tomato plots. None of the materials had negative side effects on seven species of earthworms (10).
soil treated with ground neem leaves and ground seed kernals under greenhouse conditions. Reproduction was slightly favored over a period of 13 weeks in a neem-enriched
substrate in rearing cages. Various neem products were incorporated in the upper 10-cm soil layer of tomato plots. None of the materials had negative side effects on seven species of earthworms (10).
No
significant
effects
on
other
wildlife
were
reported
(8).
ENVIRONMENTAL
FATE
Breakdown
of
Chemical
in
Soil
and
Groundwater
Potential
for
mobility
in
soil
is
very
low
for
the
formulated product . Accumulation in the environment is not expected (8).
formulated product . Accumulation in the environment is not expected (8).
Breakdown
of
Chemical
in
Surface
Water
A formulated product which contains the active ingredient azadirachtin is considered a water pollutant. It breaks down rapidly (in 100 hours) in water or light, and
will not cause long-term effects (8).
A formulated product which contains the active ingredient azadirachtin is considered a water pollutant. It breaks down rapidly (in 100 hours) in water or light, and
will not cause long-term effects (8).
Breakdown
of
Chemical
in
Vegetation
Azadirachtin
is
considered
non-phytotoxic
when
used
as
directed
(2).
PHYSICAL
PROPERTIES
AND
GUIDELINES
Azadirachtin
is
a tetranortriterpenoid
botanical
insecticide
of
the
liminoid
class
extracted
from
the
neem
tree
Azadirachta
indica.
It
is
a yellow-green
powder,
with
a strong
garlic-sulfur
odor.
Hazardous
combustion
products
include
carbon
monoxide
and
carbon dioxide (1, 2, 8, 11).
carbon dioxide (1, 2, 8, 11).
REFERENCES
1.Farm
Chemicals
Handbook.
1995.
Meister
Publishing
Co.
Willoughby,
OH.
2.Thomson,
W.T.
Agricultural
Chemicals.
Book
I:
Insecticides.
1992.
Thomson
Publications,
Fresno,
CA.
3.U.S.
Environmental
Protection
Agency.
1993.
Azadirachtin:
Tolerance
Exemption.
Federal
Register.
Vol.
58,
No.
30.
Rules
and
Regulations.
Wednesday,
February
17,
1993.
4.National
Research
Council.
1992.
Neem:
A tree
for
solving
global
problems.
National
Academy
Press,
Washington,
DC.
5.AgriDyne
Technologies,
Inc.
March,
1994.
Greenhouse
Grower.
Floritech
report:
Tough
on
pests,
easy
on
crops--and
the
environment.
AgriDyne
Technologies,
Inc.,Salt
Lake
City,
UT.
6.Grace-Sierra
Crop
Protection
Co.
1990.
Margosan-O
technical
bulletin.
Grace-Sierra
Crop
Protection
Co.,
Milpitas,
CA.
7.W.
R.
Grace
&
Co.
1991.
MSDS
for
Margosan-O.Washington
Research
Center,
Columbia,
MD.
8.Martineau,
Jess.
AgriDyne
Technologies,
Inc.January
26,
1994.
MSDS
for
Azatin-EC
Biological
Insecticide.
9.Sadre,
N.
L.,
V.
Y.
Deshpande,
K.
N.
Mendulkar
and
D.
H.
Nandal.
1983.
"Male
antifertility
activity
of
azadirachta
indica
in
different
species"
(paper
presented
at
the Proceedings of the 2nd International Neem conference, Rauischholzhausen, Germany, 1983). pp. 473-482.
the Proceedings of the 2nd International Neem conference, Rauischholzhausen, Germany, 1983). pp. 473-482.
10.Rossner,
J.
and
C.
P.
W.
Zebitz.
1986.
"Effect
of
soil
treatment
with
neem
products
on
earthworms(Lumbricidae)"
(paper
presented
at
the
Proceedings
of
the
3rd
International Neem Conference, Nairobi, 1986). pp. 627-632.
International Neem Conference, Nairobi, 1986). pp. 627-632.
11.Review
by
AgriDyne
Technologies,
Inc.
May,
1995
Disclaimer:
Please
read
the
pesticide
label
prior
to
use.
The
information
contained
at
this
web
site
is
not
a substitute
for
a pesticide
label.
Trade
names
used
herein
are
for
convenience
only.
No
endorsement
of
products
is
intended,
nor
is
criticism
of
unnamed
products
implied.
6.
Neem
Oil
On
Cattle
Tick
A
study
on
the
effect
of
neem
oil
on
the
life
cycle
of
the
cattle
tick
(Boophilus
microplus)
by
John
Farries
a report
of
a trial
undertaken
in
a dairy
herd
in
Thailand
an
addition
to
the
current
research
literature
on
neem
as
a natural
pesticide
of
interest
to
agricultural
researchers
and
practitioners
in
the
developing
world
ABOUT
THE
AUTHOR
John
Farries
has
a Scottish
Diploma
in
Agriculture
and
Dairying,
and
over
thirty
years’
experience
of
working
with
livestock.
He
has
extensive
experience
as
a farm
manager
and
has
also
worked
as
a research
adviser
in
dairy
and
beef
production
including
conducting
breeding
trials
and
collating
data.
John
worked
alongside
Thai
agriculturalists
as
a VSO
Dairy
Husbandry
Worker
at
Rachamangala
Institute
of
Technology
Agricultural
Campus,
Pitsanuloke,
Thailand,
from
1993-1996.
His
work
advising
on
the
improvement
of
the
dairy
herd,
particularly
its conception rates, as well as conducting extensive trials into pasture and grass
legumes mixtures and the use of neem as a botanical pesticide.
its conception rates, as well as conducting extensive trials into pasture and grass
legumes mixtures and the use of neem as a botanical pesticide.
ABSTRACT
Ticks
of
all
stages
were
collected
and
treated
with
solutions
of
neem
oil
diluted
in
water in concentrations of 0.1%, 0.2%, 0.4%, 0.6%, 0.8% and 1.0%. These were compared with a control of water only. It was found that in the greater dilutions, the immature ticks as well as the gravid ticks laid ticks before dying. The dilution of 1.0% had the greatest mortality with least egg laying.
water in concentrations of 0.1%, 0.2%, 0.4%, 0.6%, 0.8% and 1.0%. These were compared with a control of water only. It was found that in the greater dilutions, the immature ticks as well as the gravid ticks laid ticks before dying. The dilution of 1.0% had the greatest mortality with least egg laying.
Eggs
from
treated
and
non-treated
ticks
were
hatched
and
the
resultant
nymphs
were
also
treated
with
dilutions
of
0.1%,
0.2%,
0.4%,
0.6%,
0.8%
and
1.0%.
Viability
and
hatchability
was
affected
by
the
different
dilutions:
the
dilution
of
0.1%
had
least
effect
on
the
viability
of
the
eggs
laid
and
had
the
greatest
hatchability,
while
the
dilutions
of
0.8%
and
1.0%
had
the
greatest
effect,
with
60-75%
of
the
eggs
non-viable.
The
eggs
of
the
treated
ticks
were
smaller
and
paler
in
colour
than
those
of
the
non-treated
ticks.
The
time
of
incubation
did
not
vary
and
was
around
21
days.
Nymphs
from
eggs
of
treated
ticks
were
paler
and
had
less
mobility
than
those
from
eggs
of
untreated
ticks,
although
heat
and
light
stimulated
allstantly
by
the
alcohol
rather
than
by
the
concentration
of
neem
oil.
When
collecting
ticks
from
the
cattle,
it
was
found
that
there
were
smaller
darker
ticks
in
the
container
after
collection.
These
were
considered
to
be
male
ticks
which
had
attached
to
the
underside
of
the
female
ticks
in
the
act
of
fertilisation.
These
small
dark
ticks
were
also
more
active,
indicating
that
they
may
fertilise
more
than
one
female,
the
main
aim
of
which
is
to
engorge
with
blood
and
reproduce.
In
the
treatment,
the
small
dark
ticks
died
before
the
female
ticks.
METHOD
Eight-legged
ticks
of
immature
and
gravid
stages
were
collected
from
cattle
at
the
dairy
at
Rachamangale
Institute
of
Technology,
Pitsanuloke.
These
were
then
segregated
into
screwtop
containers.
Natural
conditions
such
as
soil
and
moisture
were
provided
for
some
ticks.
Tissue
paper
soaked
with
bovine
blood
was
also
provided.
This
did
not
prove
to
be
effective
in
feeding
any
tick
that
was
not
gravid.
Some
ticks
were
given
a dry
container
- no
natural
conditions.
These
were
usually
single
ticks
or
pair
of
ticks.
Untreated
ticks
were
watched
and
maintained
until
hatching.
Fungus
appears
to
be
the
main
predator
of
untreated
gravid
ticks,
especially
were
moisture
has
been
added.
Ticks
which
were
treated
were
in
batches
of
5-10
depending
upon
the
number
of
ticks
collected
and
available.
The
replication
tests
were
carried
out
with
greater
numbers.
The
tests
were
replicated
two
times.
Two
methods
were
used
to
treat
ticks
in
order
to
to
simulate
1. whether the tick was already on the animal when the animal was sprayed
or
2. whether the tick crawled onto the animal after spraying.
1. whether the tick was already on the animal when the animal was sprayed
or
2. whether the tick crawled onto the animal after spraying.
To
simulate
the
first
case,
the
relevant
dilution
was
brushed
onto
the
ticks
with
a brush.
For
the
second,
the
ticks
were
put
in
a screwtop
bottle
on
top
of
a tissue
soaked
with
the
relevant
dilution
of
neem
oil
and
water,
and
application
was
by
sensory
touch
of
the
tick.
The
effects
of
the
two
methods
were
relatively
similar.
In
moist
conditions,
eggs
from
untreated
ticks
develop
embryos
in
12
days.
The
eggs
from
treated
ticks
are
slower
to
develop
and
there
is
a greater
incidence
of
eggs
collapsing
and
drying
out
in
dilutions
of
0.4%,
0.6%
and
0.8%.
At
hatching,
nymphs
from
untreated
ticks
were
distributed
into
screwtop
bottles
with
tissue
paper
soaked
in
the
six
dilutions.
There
was
a control
bottle
with
water
only.
Numbers
per
bottle
varied
from
50-200
depending
on
the
replication.
Regular
counting
of
live/dead
nymphs
took
place
thereafter
until
all
nymphs
were
dead
or
had
expired
through
loss
of
energy.
When
nymphs
hatched
from
the
eggs
of
treated
ticks,
further
diluent
was
added
to
maintain
moisture
content
within
the
bottle.
Live/dead
counts
were
taken
of
these
groups
also.
RESULTS
Treated
ticks
As
the
table
shows,
the
number
of
immature
ticks
which
attempt
to
complete
their
life
cycle
by
laying
eggs
is
similar
to
those
in
the
control
group
for
all
dilutions,
except
when
treated
with
1.0%
solution.
Treatment % of ticks laying eggs Mean of 3 replications
Control 25 : 30 : 43 32%
0.1% 23 : 20 : 22 22%
0.2% 22 : 35 : 27 28%
0.4% 43 : 25 : 8 25%
0.6% 50 : 22 : 33 34%
0.8% 66 : 9 : 10 28%
1.0% 0 : 10 : 10 6%
When
hatching
and
subsequent
activity
is
considered,
there
was
a much
greater
significance
between
treatments.
Treatment Hatchability Mean Activity
Control dried out : 0 : 95 : 95 63% Highly active
0.1% 85 : 80 : 75 80% Highly active
0.2% 55 : 65 : 66 62% Highly active
0.4% 75 : 65 : 0 46% Slow to hatch, active
0.6% 50 : 60 : 12.5 41% Slow to hatch, active
0.8% 50 : 30 : 7.7 29% Slow to hatch, active
1.0% 0 : 0 : 40 13% 40% Hatch from 1 gravid tick,active
(Zero hatchability mens that no embryos developed from the eggs laid.)
The
results
of
the
treatments
from
untreated
ticks
were
analysed
for
statistical
variance
and
are
summarised
below.
ANALYSIS
OF
VARIANCE
Time (days Coefficient of variance Significant @ 1.0%
(ns = not significant)
1 18.7% 14.26
3 21.4% 12.67
6 28.9% 6.88
10 34.0% 5.11
13 45.4% 3.09 @ 5%
17 57.0% n.s.
21 70.7% n.s.
24 90.8% n.s.
27 149.0% n.s.
TREATMENTS
ns
= not
significant
* = significant at 5%
** = significant at 1%
* = significant at 5%
** = significant at 1%
Day Control 0.1 0.2 0.4 0.6 0.8 1.0
1
means
83.10
70.87
67.17
72.33
57.40
27.03
22.93
difference
- -
-12.34
ns
-15.93
ns
-10.77
ns
-25.70*
-56.07*
-60.17**
3
means
81.93
69.63
66.53
71.93
50.77
27.03
18.13
difference
- -
-12.30
ns
-15.40
ns
-10.00
ns
-31.17**
-54.90**
-63.80**
6
means
70.63
67.67
62.40
67.13
43.67
25.90
16.43
difference
- -
-2.97
ns
-8.23
ns
-3.50
ns
-26.97*
-44.73**
-54.20**
10
means
60.70
55.40
60.20
60.70
42.77
21.50
13.33
difference
- -
-5.30
ns
-0.50
ns
-0.50
ns
-17.93ns
-39.20**
-47.37**
13
means
58.50
41.50
45.77
50.33
37.20
17.07
11.50
difference
- -
-17.00
ns
-12.75
ns
-8.17
ns
-21.30
ns
-41.43**
-47.00**
17
means
45.10
35.07
42.10
43.90
33.73
11.67
8.40
difference
- -
-10.03
ns
-3.00
ns
-1.20
ns
-11.3
ns
-33.43*
-36.70*
After 17 days, the differences between treatments ceased to be significant. It is considered that there were two main reasons for this. It is accepted that after 17 days the effect of the neem oil will have diminished in spite of the closed container. The other reason is that there is a great range in the natural vitality of the newly hatched nymphs. Some ticks have more energy than others and since they are selected at random for the treatments, the law of averages dictates that there would be an average number of high vitality ticks in each treatment.
To
extrapolate
the
results
into
a practical
situation,
the
recommendation
to
spray
every
2 weeks
(14
days)
in
order
to
control
ticks
is
considered
acceptable.
At
no
stage
was
it
the
intention
of
the
experiment
to
eliminate
the
tick,
as
it
has
been
proven
that
a certain
number
of
ticks
are
essential
to
control
the
incidence
of
tick
fever
and
to
maintain
the
natural
balance.
CONCLUSION
From
the
results
of
this
experiment,
it
is
considered
that
a dilution
of
neem
oil
in
water
of
1.0%
contains
sufficient
botanical
insecticide
in
the
form
of
Azadirachtin
to
affect
the
life
cycle
and
to
control
the
cattle
tick.
It
cannot
be
emphasised
too
strongly
that
a botanical
insecticide
acts
in
a different
way
to
a chemical
insecticide.
The
results
are
not
immediate
as
is
the
case
with
chemicals,
but
there
is
a gradual
build-up
in
control
with
no
side
effects
at
the
dilutions
used
in
this
trial.
Reproduced
with
permission
from
VSO,
an
NPO
and
acknowledgements
to
Mr.
John
Farries
for
his
study
Rachelle
&
Richard
have
wonderfully
explained
herein
how
Neem
Oil
played
an
role
in
eliminating
their
children's
problem
of
Head
Lice.
We
first
came
across
neem
about
2 years
ago,
when
we
read
a magazine
article
about
this
wonderful
tree
and
all
its
life-enhancing
properties.
We
did
not
have
access
to
the
internet
then,
and
searched
as
well
as
we
could
for
some
neem
oil,
but
were
unable
to
find
anybody
that
was
selling
it
in
this
country.
We
accepted
our
defeat
and
put
it
to
the
back
of
our
minds
until
some
months
later
when
a friend
of
ours
announced
she
had
a three-week
holiday
booked
to
India.
˜I
wonder
if
you
might
do
us
a favour"
we
began,
and
told
her
of
neem
oil.
She
agreed
and
three
weeks
later
we
were
proudly
holding
our
bottle
of
thick
brown
sludge,
wondering
how
on
earth
we
were
going
to
cope
with
the
smell
of
rancid
burnt
onions
that
was
seeping
from
this
bottle.
Our
main
reason
for
wanting
neem
oil
was
to
see
how
it
would
handle
a population
of
head-lice
that
had
taken
residence
on
two
children.
We
fought
the
battle
of
continual
shampooing,
conditioning,
combing,
and
the
weeping
and
wailing
that
inevitably
ensued.
Not
to
mention
the
incessant
scratching
that
seemed
to
"catch",
just
like
the
lice
themselves.
We
were
going
through
a particularly
bad
infestation
where
you
could
see
one
of
the
children's
heads
literally
crawling
with
lice,
we
learnt
never
to
ask
her
a question
where
the
answer
was
"no",
because
if
she
shook
her
head
a deluge
of
lice
would
ceremoniously
land
on
the
floor.
How
on
earth
she
lived
with
it
we
will
never
know,
but
this
was
by
far
the
worst
case
of
it
we
had
ever
seen.
She
was
even
affectionately
nicknamed
"Mother
louse"
because
these
little
creatures
seemed
to
just
adore
her!
We
refused
to
go
down
the
route
of
organophosphates
that
are
in
all
the
proprietary
shampoos
for
lice,
as
we
were
aware
of
the
terrible
damage
these
chemicals
could
do
to
the
body's
nervous
system
and
so
neem
seemed
to
be
the
answer
to
our
prayers,
fulfilling
the
role
of
a natural,
safe
yet
effective
solution.
We
had
absolutely
no
knowledge
or
any
source
of
wisdom
for
how
to
use
this
evil-smelling
stuff
and
so
we
plastered
the
children's
heads
with
it
neat,
combed
it
through,
wrapped
their
heads
in
cling-film
and
sent
them
out
in
the
garden
to
play
for
a couple
of
hours.
They
had
a wonderful
time
chasing
each
other
about
as
"aliens"
with
their
plastic,
sticky
heads
and
little
did
we
know
that
all
the
time
Mother
Nature
was
weaving
her
magic
on
their
"uninvited
guests".
After
about
4 hours
in
total
we
applied
shampoo
onto
their
hair
and
rinsed
it
off,
followed
by
another
shampoo
and
set
to
work
combing
their
hair
through
with
a lice
comb.
To
this
day,
we
are
absolutely
astounded
by
the
results
we
witnessed.
Our
conservatory
floor
rather
looked
like
a mini
necropolis
for
hundreds
(yes
hundreds)
of
lice
that
were
combed
out,
but
they
had
all,
every
single
one
of
them
died
and
combed
easily
off
the
hair.
The
girls
were
free
at
last
of
their
"company"
and
their
hair
was
shiny
and
healthy
looking.
Whether
or
not
we
applied
it
in
the
right
way,
we
still
do
not
know,
but
we
were
desperate
to
get
rid
of
these
lice
and
had
to
resort
to
desperate
measures.There
were
certainly
NO
side
effects,
which
we
know
would
not
have
been
the
case
if
we
had gone down the "orthodox" route.
had gone down the "orthodox" route.
We
are
still
eager
to
learn
the
uses
of
neem
oil,
and
have
used
it
for
a nasty
skin
infection
that
prevented
the
need
for
antibiotics,
for
our
animals
as
a flea
treatment
and
a very
novel
use
we
have
found
is
as
a deterrent
for
thumb
sucking!
Rachelle
and
Richard
Strauss
Top
8."NEEM - THE BITTER GEM " - "KARWA AMRIT" (Hindi)
The author, Pushp K Jain, is a noted writer on Wildlife and also specialises in medicinal plants.
Excerpts from "India - Perspectives" July 1998
Introduction :- During my 31 years of service in India, conducting, among other things, leprosy control programmes and publichealth clinics, I was amazed to find a most versatile medicinal plant - NEEM - which proved to be invaluable. The following article
sums up many of my own experiences in using this plant / seed to bring healing to many sick people - even helping to diagnose victims of snake poisoning - and to help create a cleaner environment. During my years involved in caring for leprosy patients, while I did not find that NEEM has any effect on the leprosy bacillus, it is a really good cleansing agent for treating diseased skin and open sores. For this reason, it plays an important role in the production of soap, toothpaste, ointment and other medications.
However, while NEEM is well known and extensively used in India, the real potential of this remarkable plant is yet to be understood by the world in general.
-Kelli
"NEEM is one tree, the very presence of which near one's abode, is considered healthy. This large, generally evergreen tree(except in drier parts of India where it is leafless for a short period during February - March), with a broad canopy, is a common sight in most parts of India It grows wild in the Siwalik Hills in north India and in Andhra Pradesh, Tamil Nadu and Karnataka in south India. It has mostly been cultivated in drier parts of the country from where it escaped and became wild in many localities. The British in India used it extensively as a roadside and avenue tree. It has an almost straight trunk and spreading branches, covered with dark grey, cracked bark. The compound leaves are characteristic. They arise, crowded at the end of branchlets. Leaflets are alternative and opposite, oblique or subfalcate with toothed edges and pointed tips. Tender young leaves lend the tree a charming, soothing, green and shining canopy. Flowers are small, whitish or yellowish, appearing in large numbers in drooping axes from the leaf axils. Their sweet smell attracts buzzing swarms of insects as long as the bloom lasts. The green fruit, turning yellow on ripening, is small and pulpy, with a stone containing a single seed.
Almost every part of the tree is bitter and finds medicinal use, so much so that the bitterness of the tree is proverbial and it is believed that the more bitter, the better. Neem extracts possess anti-diabetic, anti-bacterial and anti-viral properties and have been used successfully in cases of stomach worms and ulcers. The tree and root barks and young fruit possess astringent, tonic and antiperiodic properties. The bark is beneficial in malaria and cutaneous diseases. Leaves are said to be discutient and their juice to
be antithelmintic. The kernels yield a greenish yellow to brown, acrid, bitter fixed oil, known as "Margosa Oil" and also called "Nimbadi Thailam". Oil from nuts and leaves is a local stimulant, insecticide and antiseptic. Flowers are stimulant, tonic and
stomachic.
The bark exudes a clear, bright, amber coloured gum known as "East India Gum", which blackens with age. The gum is a stimulant, demulcent and tonic and is useful in catarrhal and other infections. Powdered bark or its fluid extract or decoction has been successfully tried in the past by numerous European and Indian doctors in cases of intermittent and other paroxysmal fevers. The above, with the addition of Coriander and and Ginger powder or bruised Cloves or Cinnamon powder is said to be superior to
Quinine. Margosa Oil can be used as a dressing for foul ulcers, as a liniment to rheumatic affections and in headaches. It is a favourite application in tetanus, leprosy, uticaria, eczema, erysipelas, scrofula and skin diseases like ringworm, scabies, pemphigus
etc.. It cures dental and gum troubles. Applications of warm oil, taken in betel leaf, provide relief in asthma. As an insecticide, it is used against lice. Oil, sniffed for a month, while keeping on a milk diet, stops greying of hair. Powdered kernels are also used for washing hair. Leaves, in the form of pulp, paste or poultice are useful antiseptic applications to pustules, indolent, glandular swellings, boils and ulcers. A paste of leaves and dry Ginger, mixed with a little rock-salt, is applied to eyes to remove inflammation, itching and pain. Powder of the leave, with that of Symplocos Racemosa, kept in a cotton pouch, is dipped in water and the extract so obtained is used as eye-drops to alleviate eye diseases. Leaves eaten daily act as a prophylactic to scorpion sting and snake poison. They are used to diagnose snake poisoning cases. A person affected by the poison, does not find the leaves bitter ".Such is the virtue of NEEM that almost all the text of Indian Systems of Medicine describe its uses" . This Gem of a Tree is yet to be fully discovered by the World at Large.
8."NEEM - THE BITTER GEM " - "KARWA AMRIT" (Hindi)
The author, Pushp K Jain, is a noted writer on Wildlife and also specialises in medicinal plants.
Excerpts from "India - Perspectives" July 1998
Introduction :- During my 31 years of service in India, conducting, among other things, leprosy control programmes and publichealth clinics, I was amazed to find a most versatile medicinal plant - NEEM - which proved to be invaluable. The following article
sums up many of my own experiences in using this plant / seed to bring healing to many sick people - even helping to diagnose victims of snake poisoning - and to help create a cleaner environment. During my years involved in caring for leprosy patients, while I did not find that NEEM has any effect on the leprosy bacillus, it is a really good cleansing agent for treating diseased skin and open sores. For this reason, it plays an important role in the production of soap, toothpaste, ointment and other medications.
However, while NEEM is well known and extensively used in India, the real potential of this remarkable plant is yet to be understood by the world in general.
-Kelli
"NEEM is one tree, the very presence of which near one's abode, is considered healthy. This large, generally evergreen tree(except in drier parts of India where it is leafless for a short period during February - March), with a broad canopy, is a common sight in most parts of India It grows wild in the Siwalik Hills in north India and in Andhra Pradesh, Tamil Nadu and Karnataka in south India. It has mostly been cultivated in drier parts of the country from where it escaped and became wild in many localities. The British in India used it extensively as a roadside and avenue tree. It has an almost straight trunk and spreading branches, covered with dark grey, cracked bark. The compound leaves are characteristic. They arise, crowded at the end of branchlets. Leaflets are alternative and opposite, oblique or subfalcate with toothed edges and pointed tips. Tender young leaves lend the tree a charming, soothing, green and shining canopy. Flowers are small, whitish or yellowish, appearing in large numbers in drooping axes from the leaf axils. Their sweet smell attracts buzzing swarms of insects as long as the bloom lasts. The green fruit, turning yellow on ripening, is small and pulpy, with a stone containing a single seed.
Almost every part of the tree is bitter and finds medicinal use, so much so that the bitterness of the tree is proverbial and it is believed that the more bitter, the better. Neem extracts possess anti-diabetic, anti-bacterial and anti-viral properties and have been used successfully in cases of stomach worms and ulcers. The tree and root barks and young fruit possess astringent, tonic and antiperiodic properties. The bark is beneficial in malaria and cutaneous diseases. Leaves are said to be discutient and their juice to
be antithelmintic. The kernels yield a greenish yellow to brown, acrid, bitter fixed oil, known as "Margosa Oil" and also called "Nimbadi Thailam". Oil from nuts and leaves is a local stimulant, insecticide and antiseptic. Flowers are stimulant, tonic and
stomachic.
The bark exudes a clear, bright, amber coloured gum known as "East India Gum", which blackens with age. The gum is a stimulant, demulcent and tonic and is useful in catarrhal and other infections. Powdered bark or its fluid extract or decoction has been successfully tried in the past by numerous European and Indian doctors in cases of intermittent and other paroxysmal fevers. The above, with the addition of Coriander and and Ginger powder or bruised Cloves or Cinnamon powder is said to be superior to
Quinine. Margosa Oil can be used as a dressing for foul ulcers, as a liniment to rheumatic affections and in headaches. It is a favourite application in tetanus, leprosy, uticaria, eczema, erysipelas, scrofula and skin diseases like ringworm, scabies, pemphigus
etc.. It cures dental and gum troubles. Applications of warm oil, taken in betel leaf, provide relief in asthma. As an insecticide, it is used against lice. Oil, sniffed for a month, while keeping on a milk diet, stops greying of hair. Powdered kernels are also used for washing hair. Leaves, in the form of pulp, paste or poultice are useful antiseptic applications to pustules, indolent, glandular swellings, boils and ulcers. A paste of leaves and dry Ginger, mixed with a little rock-salt, is applied to eyes to remove inflammation, itching and pain. Powder of the leave, with that of Symplocos Racemosa, kept in a cotton pouch, is dipped in water and the extract so obtained is used as eye-drops to alleviate eye diseases. Leaves eaten daily act as a prophylactic to scorpion sting and snake poison. They are used to diagnose snake poisoning cases. A person affected by the poison, does not find the leaves bitter ".Such is the virtue of NEEM that almost all the text of Indian Systems of Medicine describe its uses" . This Gem of a Tree is yet to be fully discovered by the World at Large.
9.
Neem
Oil
For
Pear
Sawflies
Neem
Oil
for
control
of
Pear
Sawflies
also
known
as
Slugs
Neem Oil's Anti-feedant activity has been the main focus in this article.
Neem Oil's Anti-feedant activity has been the main focus in this article.
Neem
Oil
Offensive
Pear
sawflies,
also
known
as
pear
slugs
because
of
the
appearance
of
their
larvae,
are
pests of pears and cherries that can be of particular concern in organic production systems. Neem oil, a natural product from the Indian neem tree, is toxic to a wide variety of insects. Can neem oil be used to control pear slugs in organic orchards? PARC researchers found that neem is slightly toxic to slug larvae, but more important its
presence stops the insects from feeding. Larvae find treated cherry foliage so distasteful they don’t eat, even when nothing else is available. They would rather starve.
pests of pears and cherries that can be of particular concern in organic production systems. Neem oil, a natural product from the Indian neem tree, is toxic to a wide variety of insects. Can neem oil be used to control pear slugs in organic orchards? PARC researchers found that neem is slightly toxic to slug larvae, but more important its
presence stops the insects from feeding. Larvae find treated cherry foliage so distasteful they don’t eat, even when nothing else is available. They would rather starve.
Neem
oil
is
effective
at
very
low
doses,
and
breaks
down
rapidly.
Carefully
timed
sprays
of
neem
oil
may
prevent
feeding
by
pear
slug
larvae,
while
leaving
no
residues
on
the
leaves
or
the
fruit.
Acknowledgement:
Dr.
Mike
Smirle
10. NEEM:A POTENTIAL BIOPESTICIDE AND SOIL CONDITIONER
by Mr. Prajapati
The Neem
Azadirachta indica A.Juss. (Syn. Melia azadirachta L . ) ; Eng- Margosa tree, Neem tree; Hindi- Neem (Meliaceaae). A common roadside tree bearing small, white and sweet scented flowers. Blossoms in early April in North Indian conditions. Tree is considered a good purifier of air, due to its large leaf area. Native of Burma but grown all over India. Oilcake, obtained from seeds, is used as a fertilizer and manure. Green twigs are used as tooth brushes for cleaning teeth, and as a prophylactic for mouth and teeth complaints. Parts of the plant are used medicinally and the leaves are placed in suit cases to repel insects and to preserve woollens. An extract of leaves is used in tooth pastes and soaps Seeds yield famous margosa oil of disagreeable garlic like flavour. Oil is said to be effective in treatment of leprosy and skin diseases. Also used as a cure for manage in dogs. Leaves in poultice are used for healing of wounds. Ripe fruits are edible. Due to its bitter taste and disagreeable odour, not removed by conventional methods, neem oil has not been utilised on an industrial scale. However, a process has recently been developed to extract the bitter constituents from neem oil. Oil thus obtained has been found to be suitable for soap making and for hydrogenation. Seed oil is also used as antiseptic and for burning purposes. Stones from fruits are used as beads in rosaries and necklaces. Azadirachtin, a substance isolated from the tree, has been found to have insect repellent and insecticidal properties. Bark yields tannin. Gum exudate from the bark is used in medicines as a stimulant, and for dyeing silk. Bark is useful in fever, nausea, vomitting and skin disease. Bitter principles of neem oil are reported to have been obtained by extraction with alcohol. The main component of the oil is nimbidin which is very bitter. Nimbidin is used for making several pharmaceutical preparations including emulsions, liquors, ointments, medicinal cosmetics such as lotions, shampoos, creams, hair tonics and gargles. Timber is used for agricultural implements and furniture.
Besides above Neem products ? Neem EC and Neem UCA have also been produced as plant growth promoter and soil conditioning agent.
NEEM EC
NEEM EC is the general- purpose botanical pesticide of choice for organic agriculture . NEEM EC is widely used in several countries around the world today either singly in Integrated Pest Management or in conjunction with synthetic pesticides. Amongst the other known botanical pesticides such as Rotenone and Pyrethrins, NEEM EC is superior due to reasons cited below. Research has shown that neem extracts can influence nearly 200 spices of insects. It is significant that some of these pests are resistant to pesticides, or are inherently difficult to control with conventional pesticides (floral thrips, diamond back moth and several leaf miners).NEEM EC belongs to the category of medium to broad spectrum pesticides. NEEM EC works by intervening at several stages of the life of an insect. It does not kill the pests instantaneously but incapacitates it in several other ways.
Mode of Action : Neem acts as a biopesticide at different levels and ways. This is very important since the farmer is used to the knock out effect of chemical pesticides. Neem does not exhibit this type of effect on pests but affects them in several other ways.
Mainly: Oviposition Deterrent Insect Growth Regulation: It is a very interesting property of neem products and unique in nature, since it works on juvenile hormone. The insect larva feeds when it grows, it sheds the old skin and again starts growing. This particular shedding of old skin is the phenomenon of ecdysis or moulting is governed by an enzyme ecdysone. When the neem components, especially Azadirachtin enter into the body of larvae, the activity of ecdysone is suppressed and the larva fails to moult, remains in the larval stage and ultimately dies. If the concentration of Azadirachtin is not sufficient, the larva manages to enter the pupal stage but dies at this stage and if the concentration is still less the adult emerging from the pupa is 100 % malformed, absolutely sterile without any capacity for reproduction.
Feeding Deterrent: The most important property of neem is feeding deterrence. When an insect larva sits on the leaf, the larva is hungry and it wants to feed on the leaf. This particular trigger of feeding is given through the maxillary glands give a trigger, peristalsis in the alimentary canal is speeded up, the larva feels hungry and its starts feeding on the surface of the leaf. When the leaf is treated with neem product, because of the presence of azadirachtin, salanin and melandriol there is an anti ? peristalitic wave in the alimentary canal and this produces something similar to vomiting sensation in the insect. Because of this sensation the insect does not feed on the neem treated surface. Its ability to swallow is also blocked.
Oviposition Deterrent: Another way in which neem reduces pests is not by allowing the female to deposits eggs. This property is known as Oviposition deterrence, and comes in very handy when the seeds in storage are coated with neem Kernel powder and neem oil. The seeds or grains obtained from the market are already infested with some insects. Even these grains could be treated with neem seed kernel extract or neem oil; after this treatment the insects will not feed on them. There will be no further damage to the already damaged grains and at the same time when the female comes to the egg laying period of its life cycle, egg laying is prevented.
Other pesticidal activity includes of need include (1) The formation of chitin (exoskeleton) is also inhibited. (2) Mating as well as sexual communication is disrupted.(3) Larvae and adults of insects are repelled. (4) Adults are sterilised. (5) larvae and adults are poisoned.
Use of neem products does not give immediate results like chemical insecticides. Some patience is required after application of neem products.
Chemistry of Ingredients of Neem
Neem plants, as do all other plants, contain several thousands of chemical constituents.Of special interest are the terpenoids are known from different parts of the neem plant. Of its biological constituents the most active and well studied compound is Azadirachtin. However, in most traditional preparations of neem as pesticide or medicine a mixture of neem chemicals are present and provide the active principles. Several different kinds of azadirachtins (A to K) have been isolated, the most abundant of which is Azadirachtin ? A. The neem terpenoids are present in all parts of the plant, in the living tissues. Recently, the site of synthesis and accumulation of the neem chemicals has been identified as secretory cells. Secretory cells are most abundant in the seed kernels. The secretory cells can be seen with iodine solution. Besides the terpenoids, neem also contains more than 20 sulphurous compounds responsible for the characteristic smell of crushed seeds and neem oil.
Toxicity: In toxicological studies carried out in the USA and Germany, different neem product were neither mutagenous nor cancerogenic, and they did not produce any skin irritations or organic alternations to mice and rates even at high concentrations. In another Canadian study, Neem was found to be harmless to Aquatic invertebrates and other non-target species.
Benefits: Neem Biopesticide (Emulsifiable Concentrate) is well suited for an ? Integrated Pest Management? (IPM) Program because of the following salient features:(1) Neem Pesticide is a natural product, absolutely non toxic, 100% biodegradable and environment mentally friend. (2) It is suited for mixing with other synthetic pesticide and in fact enhances their action. (3) None or lesser quantity of synthetic pesticides need to be used, thereby reducing the environmental load. (4) Several synthetic pesticides being single chemical compounds cause easy development of resistant species of pests. Neem consists of several compounds hence development of resistance is impossible. (5) Neem does not destroy natural predators and parasites of pests thereby allowing these natural enemies to keep a check on the pest population. (6) Neem also has systemic action and seedlings can absorb and accumulate the neem compounds to make the whole plant pest resistant. (7) Neem has a broad spectrum of action active on more than 200 spices of pests. (8) Neem is harmless to non target and beneficial organisms like pollinators, honey bees, mammals and other vertebrates.
Following are the target insects of neem:
COMMON NAME SCIENTIFIC NAME
American boll worm Heliothis armigera
Oriental armyworm Mythimna separate
Angoumis grain moth Sitorega cerealella
Pink Cotton boll worm Petinophora gossypiella
Bark eating caterpillar Indarbela quadrinotata
Pod fly Melanogromyza obtusa
Beet leaf bug Piesma quqdratum
Pulse beetle Callosobruchus chinensis
Brown planthopper Nilaparvata lugens
Pulse bruchid Callosbruchus maculates
Cabbage butterfly Pieris brassicae
Red boll worm Rabila frontalis
Chafer beetle Apogonia blancharid
Red hairy caterpillar Amsacta albistriga
Citrus leafminer Phyllocnistis citrella
Reniform nematode Rotylenchulus reinform
Confused flour beetle Tribolium confusum
Rhinoceros beetle Oryctes rhinoceros
Corn aphid Rhopaloispum maidis
Rice moth Corcyra cephalonica
Cotton aphid Aphis gossypii
Rice skipper Pelopidas mathias
Dessert locust Schistocera gregaria
Root knot nematode Melodidogyne incognita
Diamond black moth Plutella xylostella
Root knot nematode Meloidogyne javanica
Diamond moth Plutella maculipennis
Root lesion nematode Pratylenchus genus
Gall midge Orseolis oryzae
Rust red flour beetle Tribolium castaneum
Grain borer Rhizopertha dominica
Saw toothed grain beetle Oryzaephilus surinamensis
Gram / pod borer caterpillar Heloithis armigera
Scale insect Saissetia nigra
Green leafhopper Nephotettix appicalis
Serpentine leafminer Liriomyza trifolli
Green peach aphid Myzus persicae
Shoot/ fruit borer Earias vittela
Groundnut leafminer Stomopteryx nertaria
Seleron persicae Spotted boll worm
(cotton boll worm ) Erias fabia, E. insulana E. vitella
Groundnut leafminer Stomopteryx netaria
Stem borer Scirpophaga incertulas
Gypsy moth Lymantria dispar
Stem fly Melanagromyza phaseoli
Hairy caterpillar Amsacta moorei
Stunt nematode Tylenchorhynchus brassicae
Khapra beetle Trogoderma granarium
Sugarcane aphid Melanaphis sacchaari
Leaf folder / roller Cnaphalocrocis medicella
Surface grasshopper Chrotogonus trachypterus
Leafminer Aproaerema modicella
Termite Microtermes species
Leafhopper Nephotettix virescenes
Tobacco caterpillar Spodoptera litura
Lesser grain borer Rhizzopertha dominica
White backed planthopper Sogatella furcifera
Mexican bean beetle Epilachna variverstis
White fly Bemisia tabaci
Migratory locust Locusta migratoria
Mustard aphid Lipaphis erysimi
Mustard saw fly Athalia lugens proxima
Mustard webworm Crocidomia binotalis
NEEM UCA
Urea is the major source of nitrogenous fertiliser used in Agriculture. It is estimated that out of the total quantity of urea applied to crops, about 50- 70% is lost in various forms, thereby reducing the availability of nitrogen to crops. There is an age old practice in India of blending neem cake with urea. Based on this principle is our Urea coating agent NEEM UCA, a concentrated easy to use formulation. When NEEM UCA IS coated on urea, it forms a fine coating and protects the loss of Nitrogen by denitrification ensuring regulated continuous availability of nitrogen for a longer period, as per the requirement of crops.
Mode of Action: When uncoated urea is applied to the soil, the urea (Amide) nitrogen is rapidly converted to ammoniacal nitrogen and subsequently to nitrite and nitrate forms. Nitrogen in these forms, besides being absorbed by plants, is also rapidly lost from the soil due to leaching, run off, volatilization and denitrification. When NEEM UCA coated urea is applied to soil, the neem triterpenes inhibit the activity of nitrifying bacteria resulting in delayed transformation of ammoniacal nitrogen into nitrite nitrogen. This ensures slow and continuous availability of nitrogen matching the requirements of crop plant during their life cycle.
Benefits: (1) Ready to use, economical and easy to apply. (2) Ensures slow and continuous availability of nitrogen to crops. (3) Reduces nitrogen loss from urea due to leaching and denitrification. (4) Protects crops from soil borne pests.
Method of Application: (1) Spread 50 Kg urea in the shade on a clean surface. (2) Mix evenly 250 gm NEEM UCA ensuring proper spreading on urea. (3) Rub urea NEEM UCA thoroughly by hand to get a uniform coating. For larger quantities of urea, suitable mixers can be used. (4) Allow coated urea to dry till it is free flowing and ready to use.
Top
Cockroaches
could
be
spreading
SARS
REUTERS[
TUESDAY,
APRIL
08,
2003
05:45:22
PM
]
HONG
KONG/SINGAPORE:
Cockroaches
may
have
carried
a deadlyflu-like virus through a Hong Kong apartment block, a top health official said on Tuesday as the disease spread to one of the city's crowded new towns.
At least three more people died in Beijing from SARS than officially reported, doctors in Beijing said on Tuesday as fears spread and hospitals disclosed suspected cases not previously revealed.
Hong Kong Deputy Director of Health Leung Pak-yin told a radio programme cockroaches may have carried infected waste from sewage pipes into apartments at Amoy Gardens in densely populated Kowloon district.
If proved true, it would represent an alarming development in the swiftly spreading epidemic in Hong Kong, a city of seven million people filled with densely populated apartment blocks.
"The drainage may be the reason. It is possible that the cockroaches carried the virus (from the drainage pipes) into the homes," Leung said.
SARS raced through a block in Amoy Gardens in late March, infecting nearly 300 people and forcing residents in the building and others in the complex to flee in panic. The speed of the outbreak has baffled health officials.
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