Tuesday 11 September 2012

Air pollution ups risk of repeated heart attacks by 40%

WASHINGTON: High air pollution increases the risk of repeated heart attacks in cardiac patients by over 40 percent, a Tel Aviv University researcher has claimed.

Air pollution, which poses a serious danger to the environment, is also a major health risk, associated with respiratory infections and heart diseases.Cardiac patients living in high pollution areas were found to be over 40 percent more likely to have a second heart attack when compared to patients living in low pollution areas, according to Dr. Yariv Gerber of TAU's School of Public Health at the Sackler Faculty of Medicine.

"We know that like smoking cigarettes, air pollution also affects the inflammatory system. If you are talking about long-term exposure and an inflammatory system that is irritated chronically, pollution may well be involved in the progression of atrial sclerosis that leads to cardiac arrests," Dr. Gerber said.

Conducted in association with Prof. Yaacov Drory and funded by the Environmental and Health Fund in Jerusalem, the research was presented at the San Diego Epidemiological Meeting of the American Heart Association in March and the Annual Meeting of the Israeli Heart Society in April.The goal of this study, Dr. Gerber said, was to quantify that association and determine the long-term effects of air pollution on myocardial infarction (MI) patients.

Their study followed 1,120 first-time MI patients who had been admitted to one of eight hospitals in central Israel between 1992 and 1993, all of whom were under the age of 65 at the time of admittance.The patients were followed up until 2011, a period of 19 years.Air quality was measured at 21 monitoring stations in areas where the patients lived, and analyzed by a group of researchers at the Technion in Haifa.

After adjusting for other factors such as socio-economic status and disease severity, the researchers identified an association between pollution and negative clinical outcomes, including mortality and recurrent vascular events such as heart attack, stroke and heart failure.

Compared to patients who lived in areas with the lowest recorded levels of pollution, those in the most polluted environment were 43 percent more likely to have a second heart attack or suffer congestive heart failure and 46 percent more likely to suffer a stroke.The study also found that patients exposed to air pollution were 35 percent more likely to die in the almost 20 year period following their first heart attack than those who were exposed to lower levels of pollution.

According to Dr. Gerber, the true impact of air pollution might be even stronger than this study shows.

"Our method of assessing exposure does have limitations. Because we are using data from monitoring stations, it's a crude estimate of exposure, which most likely leads to an underestimation of the association," he warned. Doctors should be making their patients aware of the risks of living in high pollution areas, suggesting that they work to limit their exposure, Dr. Gerber suggests.

Establishing the connection between air pollution and long-term risk for patients with cardiovascular diseases was an important step towards that goal.

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